Losartan Potassium: Management of hypertension and may have a role in patients who develop cough with angiotensin-converting enzyme (ACE) inhibitors.
Hydrochlorothiazide: Treatment of edema associated with heart failure and renal or hepatic disorder. It is also used in hypertension, either alone or together with other antihypertensives such as ACE inhibitors and β-blockers. Also, for treatment of edema accompanying premenstrual syndrome, prevention of water retention associated with corticosteroid and estrogens, treatment of diabetes insipidus and prevention of renal calculus formation in patients with hypercalciuria.